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Chem Impex
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Product Information

Product Name
Fmoc-glycine pentafluorophenyl ester
Brand Name
Chem Impex
Product Number
02417
CAS
86060-85-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2733282
IUPAC Name
(2,3,4,5,6-pentafluorophenyl) 2-(9H-fluoren-9-ylmethoxycarbonylamino)acetate
InChI Key
LBSDTBJWUJIFBO-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)OC4=C(C(=C(C(=C4F)F)F)F)F

Application

Fmoc-glycine pentafluorophenyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of glycine residues with enhanced stability and reactivity.

Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, particularly in creating compounds with improved bioavailability.

Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other compounds, which is essential in diagnostics and therapeutic applications.

Research in Protein Engineering: Researchers utilize this ester in studies aimed at modifying protein structures, which can lead to advancements in enzyme activity and specificity.

Fluorinated Compound Research: Its pentafluorophenyl group allows for the exploration of fluorinated compounds, which can exhibit unique properties beneficial in materials science and chemical reactions.

References Data Source From Pubchem

High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material

Publication Name: Nature Communications
Publication Date: 2016-06-14
DOI: 10.1038/ncomms11844

Kombinatorische Chemie im hochdichten Arrayformat

Publication Name: BIOspektrum
Publication Date: 2016
DOI: 10.1007/s12268-016-0720-1

Effect of core epitope modification on the antibody recognition of a MUC2 mucin peptide

Publication Name: Molecular Diversity
Publication Date: 2012-02
DOI: 10.1007/s11030-012-9362-5

Antibody Epitope Mapping Using Arrays of Synthetic Peptides

Publication Name: Antibody Engineering
Publication Date: 2003-12-05
DOI: 10.1385/1-59259-666-5:443

Cumulative influence of elastin peptides and plasminogen on matrix metalloproteinase activation and type I collagen invasion by HT-1080 fibrosarcoma cells

Publication Name: Clinical & Experimental Metastasis
Publication Date: 2002-03
DOI: 10.1023/a:1014547324918