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Sku CI01236_25_G
Chem Impex
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Product Information

Product Name
5-Azacytidine
Brand Name
Chem Impex
Product Number
01236
CAS
320-67-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
9444
IUPAC Name
4-amino-1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-1,3,5-triazin-2-one
InChI Key
NMUSYJAQQFHJEW-KVTDHHQDSA-N
SMILES
C1=NC(=NC(=O)N1C@H2C@@H(C@@H(C@H(O2)CO)O)O)N

Application

5-Azacytidine is widely utilized in research focused on:

Cancer Treatment: This compound is primarily used in oncology to treat certain types of cancer, particularly myelodysplastic syndromes and acute myeloid leukemia, by reactivating silenced genes and promoting normal cell differentiation.

Epigenetics Research: It serves as a crucial tool for studying epigenetic modifications, allowing researchers to understand how DNA methylation affects gene expression and cellular behavior.

Stem Cell Biology: 5-Azacytidine is applied in stem cell research to induce pluripotency in somatic cells, providing insights into regenerative medicine and potential therapies for degenerative diseases.

Drug Development: The compound is used in the development of new therapeutic agents, particularly in the field of epigenetic drugs, offering a novel approach to treating various diseases by targeting gene regulation.

Gene Therapy: It is utilized in gene therapy applications to enhance the expression of therapeutic genes, making it a valuable asset in developing innovative treatments for genetic disorders.

References Data Source From Pubchem

[Treatment-refractory ulcer of the right lower leg]

Publication Name: Dermatologie (Heidelberg, Germany)
Publication Date: 2026-05
DOI: 10.1007/s00105-026-05663-9

Correction: What’s in a name? Metabolite identification: challenges and pitfalls in untargeted metabolomics

Publication Name: Metabolomics : Official journal of the Metabolomic Society
Publication Date: 2026-03-26
DOI: 10.1007/s11306-025-02387-0|10.1007/s11306-026-02418-4

Computer-aided drug design in acute myeloid leukemia: a comprehensive review of advances, challenges, and future prospect

Publication Name: Journal of Computer-Aided Molecular Design
Publication Date: 2026-03-03
DOI: 10.1007/s10822-026-00771-z

A narrative review of mutant isocitrate dehydrogenase AML in Japan based on experience with ivosidenib in AGILE

Publication Name: International Journal of Hematology
Publication Date: 2026-03-03
DOI: 10.1007/s12185-026-04175-5

Clinical and immunological implications of lymphocyte-activation gene 3 expression in metastatic colorectal cancer

Publication Name: Cancer immunology, immunotherapy : CII
Publication Date: 2026-03-03
DOI: 10.1007/s00262-026-04344-9