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Chem Impex
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Product Information

Product Name
Cytidine 5'-diphosphocholine sodium salt
Brand Name
Chem Impex
Product Number
37755
CAS
33818-15-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
36605
IUPAC Name
sodium (2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-ylmethoxy-oxidophosphoryl 2-(trimethylazaniumyl)ethyl phosphate
InChI Key
YWAFNFGRBBBSPD-OCMLZEEQSA-M
SMILES
CN+(C)(C)CCOP(=O)(O-)OP(=O)(O-)OCC@@H1C@H(C@H(C@@H(O1)N2C=CC(=NC2=O)N)O)O.Na+

Application

Cytidine 5'-diphosphocholine sodium salt is widely utilized in research focused on:

Neuroscience Research: This compound is often used to study neuronal signaling and membrane dynamics, helping researchers understand the role of phospholipids in brain function.

Pharmaceutical Development: It serves as a key ingredient in formulations aimed at enhancing cognitive function and memory, making it valuable in the development of nootropic drugs.

Cell Culture Applications: Cytidine 5'-diphosphocholine sodium salt is used in cell culture media to promote cell growth and differentiation, particularly in neuronal cell lines.

Cardiovascular Studies: Researchers utilize this compound to investigate its effects on lipid metabolism and its potential protective roles in cardiovascular health.

Biochemical Assays: It is employed in various biochemical assays to measure enzyme activity related to phospholipid metabolism, providing insights into cellular processes.

References

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening

Publication Name: SLAS discovery : advancing life sciences R & D
Publication Date: 2020-01
DOI: 10.1177/2472555219873068

A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein

Publication Name: Molecular Pharmacology
Publication Date: 2019-11
DOI: 10.1124/mol.119.115964