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Chem Impex
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Product Information

Product Name
N4-Benzoylcytidine
Brand Name
Chem Impex
Product Number
00878
CAS
13089-48-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
10066259
IUPAC Name
N-1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-2-oxopyrimidin-4-ylbenzamide
InChI Key
BNXBRFDWSPXODM-BPGGGUHBSA-N
SMILES
C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C@H3C@@H(C@@H(C@H(O3)CO)O)O

Application

N4-Benzoylcytidine is widely utilized in research focused on:

Nucleic Acid Research: This compound serves as a valuable building block in the synthesis of modified nucleotides, which are crucial for studying RNA structure and function.

Antiviral Drug Development: Its unique structure allows researchers to explore potential antiviral therapies, particularly against RNA viruses, enhancing drug efficacy and specificity.

Biochemical Assays: N4-Benzoylcytidine is employed in various assays to investigate enzyme activity related to nucleic acid metabolism, providing insights into cellular processes.

Pharmaceutical Formulations: It can be incorporated into drug formulations to improve the stability and bioavailability of therapeutic agents, making treatments more effective.

Genetic Engineering: The compound is used in gene editing technologies, facilitating the development of precision medicine approaches by enabling targeted modifications in genetic material.

References Data Source From Pubchem

Synthesis of N 4-acetylated 3-methylcytidine phosphoramidites for RNA solid-phase synthesis

Publication Name: Monatshefte für Chemie - Chemical Monthly
Publication Date: 2022-02-22
DOI: 10.1007/s00706-022-02896-x

Dynamics-Function Analysis in Catalytic RNA Using NMR Spin Relaxation and Conformationally Restricted Nucleotides

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2021
DOI: 10.1007/978-1-0716-0716-9_11

Light-controlled gene silencing in zebrafish embryos

Publication Name: Nature Chemical Biology
Publication Date: 2007-08-23
DOI: 10.1038/nchembio.2007.30

Phosphorylation of Uridine and Cytidine Nucleoside Analogs by Two Human Uridine-Cytidine Kinases

Publication Name: Molecular Pharmacology
Publication Date: 2001-05-01
DOI: 10.1016/s0026-895x(24)12578-3|10.1124/mol.59.5.1181

Protecting Groups in Oligonucleotide Synthesis

Publication Name: Protocols for Oligonucleotide Conjugates
Publication Date: 1994
DOI: 10.1007/978-1-59259-513-6_1