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Product Information

Product Name
4-(Trifluoromethyl)benzoic acid
Brand Name
Chem Impex
Product Number
45386
CAS
455-24-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
9966
IUPAC Name
4-(trifluoromethyl)benzoic acid
InChI Key
SWKPKONEIZGROQ-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1C(=O)O)C(F)(F)F

Application

4-(Trifluoromethyl)benzoic acid is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, enhancing the efficacy of drug formulations through its unique trifluoromethyl group.

Material Science: It is used in the production of high-performance polymers and resins, providing improved thermal stability and chemical resistance, which is crucial for applications in electronics and automotive industries.

Agricultural Chemicals: The compound is involved in the formulation of agrochemicals, helping to create more effective herbicides and pesticides that target specific pests while minimizing environmental impact.

Analytical Chemistry: It acts as a reagent in various analytical techniques, including chromatography, where it aids in the separation and identification of complex mixtures.

Fluorinated Compounds Research: Researchers utilize it to explore the properties and applications of fluorinated compounds, which are known for their unique chemical behavior and potential in developing new materials.

References Data Source From Pubchem

Design, synthesis and biological evaluation of 1H-indazole derivatives as InhA inhibitors and anticancer agents

Publication Name: Journal of Chemical Sciences
Publication Date: 2026-02-20
DOI: 10.1007/s12039-025-02468-6

Design and synthesis of novel quinazoline derivatives as KDM6B selective inhibitors

Publication Name: Molecular Diversity
Publication Date: 2025-12-19
DOI: 10.1007/s11030-025-11422-0

Oxadiazoles as multi-target therapeutic agents in Alzheimer’s Disease: A review of cholinesterase, MAO, β-Secretase, and Aβ aggregation inhibition

Publication Name: Journal of Saudi Chemical Society
Publication Date: 2025-11
DOI: 10.1007/s44442-025-00036-8

Quantification of the amount of surface groups of aminated silica nano- and microparticles utilizing a fluorine tag and HR-CS-GFMAS

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2025-09-22
DOI: 10.1007/s00216-025-06107-4

Energy-transfer photoproximity labelling in live cells using an organic cofactor

Publication Name: Nature Chemistry
Publication Date: 2025-09-17
DOI: 10.1038/s41557-025-01931-8