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Product Information

Product Name
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido2,3-dpyrimidine-2,4,7(1H,3H,8H)-trione
Brand Name
ChemScene
Product Number
CS-M0422
CAS
871700-24-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
59717004
IUPAC Name
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido2,3-dpyrimidine-2,4,7-trione
InChI Key
MHHFXMZMCYWCJQ-UHFFFAOYSA-N
SMILES
CC1=C(C2=C(N(C1=O)C)N(C(=O)N(C2=O)C3CC3)C4=C(C=C(C=C4)I)F)O

References

Identification and synthesis of potential process-related impurities of trametinib: an anti-cancer drug

Publication Name: Chemical Papers
Publication Date: 2022-11-07
DOI: 10.1007/s11696-022-02570-w

Synthetic Approaches to Contemporary Drugs that Contain the Cyclopropyl Moiety

Publication Name: Synthesis
Publication Date: 2020-03-16
DOI: 10.1055/s-0039-1690058

Trametinib

Publication Name: Pharmaceutical Substances
Publication Date: 2014