$119.00
Available on backorder. No lead time available. Please request a quote.
Sku 15-3035-50MG
STREM
| Technical Notes: 1.Novel mono-phosphine Buchwald ligand that supports a catalyst of improved stability. The GPhos-derived catalyst exhibits improved performance for room temperature c N cross coupling reactions between a broad scope of primary amines and aryl halides.1 The ligand is designed to promote C-N cross coupling across a wide range of substrate classes with low catalyst loadings. It shows an improved relative rate of productive catalysis versus catalyst deactivation compared to previous catalysts. TheGPhos-supported catalyst exhibits better reactivity than previous catalysts both under ambient conditions and at elevated temperatures. Its use allows for the coupling of a variety of primary amine and aniline nucleophiles, including (1) unhindered, (2) five-membered-ring N-heterocycle -containing, and (3) a-tertiary primary amines, each of which previously required a different catalyst to achieve optimal results. The GPhos-supported catalyst is also well suited for coupling electron-deficient anilines as well as N-heterocycle containing aryl halides andamines. References: 1. J Am Chem Soc. 2020 142 35 15027 15037 |
![Tris[μ-[2-amino-1,4-benzenedicarboxylato(2-)-κO1:κO'1]]diaquachloro-μ3-​oxotri-aluminum MOF, MIL-101(Al)-NH2| CAS: 1404201-64-4](http://www.jk-sci.com/cdn/shop/products/13-3060_200x200_crop_center.gif?v=1642832309)
