N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]thiourea, 95%, (99% ee)

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Sku 07-6333-50MG
STREM
Technical Notes:
1.Friedel-Crafts Alkylation- access to optically active 2-indolyl-1 -nitro derivatives by enantioselective Friedel- Crafts alkylation of indoles with nitroalkenes (R1= R2=- H, R3= Ph).
2.Conjugate Addition- Conjugate addition of O-protected hydroxylamines to pyrazole -derived enoates
proceeds with high efficiency and enantioselectivity.
References ：
1. Angew. Chem Int. Ed, 2005, 44, 6576-6579. J. Ãm. Chem. Soc., 2007, 129, 8064 -8065.