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Sku CI28736_5_G
Chem Impex
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Product Information

Product Name
2-Fluoropyridine-5-boronic acid
Brand Name
Chem Impex
Product Number
28736
CAS
351019-18-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2783397
IUPAC Name
(6-fluoro-3-pyridinyl)boronic acid
InChI Key
OJBYZWHAPXIJID-UHFFFAOYSA-N
SMILES
B(C1=CN=C(C=C1)F)(O)O

Application

2-Fluoropyridine-5-boronic acid is widely utilized in research focused on:

Synthetic Chemistry: This compound serves as a key building block in the synthesis of various pharmaceuticals and agrochemicals, enabling the development of new drugs with enhanced efficacy.

Drug Discovery: It is employed in medicinal chemistry for the design of novel compounds, particularly in targeting specific biological pathways, which can lead to breakthroughs in treatment options.

Material Science: The compound is used in the development of advanced materials, including polymers and coatings, which can exhibit improved properties such as durability and resistance to environmental factors.

Bioconjugation: It plays a significant role in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, facilitating studies in biochemistry and molecular biology.

Analytical Chemistry: This boronic acid derivative is utilized in various analytical methods, including chromatography and spectroscopy, to enhance the detection and quantification of specific analytes in complex mixtures.

References

New fused pyrroles with rA1/A2A antagonistic activity as potential therapeutics for neurodegenerative disorders

Publication Name: Molecular Diversity
Publication Date: 2021-11-05
DOI: 10.1007/s11030-021-10327-y

Synthesis and biological evaluation of selected 7-azaindole derivatives as CDK9/Cyclin T and Haspin inhibitors

Publication Name: Medicinal Chemistry Research
Publication Date: 2020-05-22
DOI: 10.1007/s00044-020-02560-1

Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expression

Publication Name: EJNMMI Radiopharmacy and Chemistry
Publication Date: 2019-01-10
DOI: 10.1186/s41181-018-0054-z

First Identification of Boronic Species as Novel Potential Inhibitors of the Staphylococcus aureus NorA Efflux Pump

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2014-02-19
DOI: 10.1021/jm401808n

Discovery of Boronic Acids as Novel and Potent Inhibitors of Fatty Acid Amide Hydrolase

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2008-11-05
DOI: 10.1021/jm801051t