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Product Information

Product Name
Pyridine-3-carboxylic acid 1-oxide
Brand Name
Chem Impex
Product Number
26991
CAS
2398-81-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
16976
IUPAC Name
1-oxidopyridin-1-ium-3-carboxylic acid
InChI Key
FJCFFCXMEXZEIM-UHFFFAOYSA-N
SMILES
C1=CC(=CN+(=C1)O-)C(=O)O

Application

Pyridine-3-carboxylic acid 1-oxide is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and anti-cancer agents.

Agricultural Chemicals: It is used in formulating agrochemicals, enhancing crop protection products by improving their efficacy and stability.

Analytical Chemistry: The compound is employed as a reagent in analytical methods, aiding in the detection and quantification of other substances in complex mixtures.

Material Science: Pyridine-3-carboxylic acid 1-oxide is utilized in the production of specialized polymers and resins, contributing to materials with enhanced thermal and chemical resistance.

Biochemical Research: It plays a role in studying enzyme activity and metabolic pathways, providing insights into biochemical processes and potential therapeutic targets.

References

Design and Spectral Validation of RAD51 Inhibitors Based on BRC4 (1523-1546)

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 2024-06
DOI: 10.1007/s11094-024-03163-5

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome

Publication Name: Cell Reports
Publication Date: 2021-04-27
DOI: 10.1016/j.celrep.2021.109040

Good pyridine hunting: a biomimic compound, a modifier and a unique pharmacophore in agrochemicals

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2020-12
DOI: 10.1007/s10593-020-02843-w

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Publication Name: Proceedings of the National Academy of Sciences of the United States of America
Publication Date: 2020-11-23
DOI: 10.1073/pnas.2005463117