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Sku CI21154_5_G
Chem Impex
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Product Information

Product Name
5-Nitro-1H-indole-3-carbaldehyde
Brand Name
Chem Impex
Product Number
21154
CAS
6625-96-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
246039
IUPAC Name
5-nitro-1H-indole-3-carbaldehyde
InChI Key
PHKYMSLVWLYDKP-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1N+(=O)O-)C(=CN2)C=O

Application

5-Nitro-1H-indole-3-carbaldehyde is widely utilized in research focused on:

Synthetic Organic Chemistry: This compound serves as a key intermediate in the synthesis of various biologically active molecules, aiding researchers in developing new pharmaceuticals.

Drug Development: Its unique structure allows for modifications that can lead to the discovery of novel drug candidates, particularly in the treatment of cancer and infectious diseases.

Fluorescent Probes: The compound can be used to create fluorescent probes for biological imaging, enhancing the ability to study cellular processes in real-time.

Material Science: It is applied in the development of advanced materials, including polymers and nanomaterials, which can be utilized in electronics and coatings.

Biochemical Research: The compound is valuable in studying enzyme interactions and metabolic pathways, providing insights into biological functions and disease mechanisms.

References

Unveiled reactivity of masked diformylmethane with enamines forming resonance-assisted hydrogen bonding leads to di-meta-substituted pyridines

Publication Name: Communications Chemistry
Publication Date: 2024-06-28
DOI: 10.1038/s42004-024-01228-w

The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions

Publication Name: Topics in current chemistry (Cham)
Publication Date: 2022-04-25
DOI: 10.1007/s41061-022-00379-5

Trichloroisocyanuric acid and NaNO2 mediated nitration of indoles under acid-free and Vilsmeier–Haack conditions: synthesis and kinetic study

Publication Name: SN Applied Sciences
Publication Date: 2019-08-08
DOI: 10.1007/s42452-019-1023-1

One-Pot Four Component Synthesis of 3-Amino-1-(1H-indol-2-yl)-5,10-dioxo-5,10-dihydro-1H-pyrazolo[1,2-b]phthalazine Derivatives Mediated by [DBUH][OAc]

Publication Name: Russian Journal of General Chemistry
Publication Date: 2018-09
DOI: 10.1134/s1070363218090219