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Sku CI20841_1_G
Chem Impex
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Product Information

Product Name
N-p-Tolyl-guanidine
Brand Name
Chem Impex
Product Number
20841
CAS
54015-04-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
409364
IUPAC Name
2-(4-methylphenyl)guanidine
InChI Key
PKQYVFHRKFDVCH-UHFFFAOYSA-N
SMILES
CC1=CC=C(C=C1)N=C(N)N

Application

N-p-Tolyl-guanidine is widely utilized in research focused on:

Pharmaceutical Development: This compound is explored for its potential as a therapeutic agent, particularly in the treatment of neurological disorders due to its ability to modulate neurotransmitter systems.

Analytical Chemistry: It serves as a reagent in various analytical methods, aiding in the detection and quantification of specific compounds in complex mixtures.

Polymer Science: N-p-Tolyl-guanidine is used as an additive in polymer formulations, enhancing properties like thermal stability and mechanical strength.

Agricultural Chemistry: The compound is investigated for its role in developing agrochemicals, particularly as a potential growth regulator for crops.

Biochemical Research: It is utilized in studies related to enzyme inhibition, providing insights into enzyme mechanisms and potential applications in drug design.

References

A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3)

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2017-09-15
DOI: 10.1016/j.bmcl.2017.08.008

Cyclocondensation of unsymmetrical perfluoroalkyl-substituted β-diketones with urea, thiourea, and guanidine

Publication Name: Russian Journal of Organic Chemistry
Publication Date: 2008-04
DOI: 10.1134/s1070428008040039

New Bis(2-aminoimidazoline) and Bisguanidine DNA Minor Groove Binders with Potent in Vivo Antitrypanosomal and Antiplasmodial Activity

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2008-02-01
DOI: 10.1021/jm7013088

Reaction of N2-Acylamidines with Amidine Derivatives

Publication Name: Science of Synthesis
Publication Date: 2004

The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2001-06-18
DOI: 10.1016/s0960-894x(01)00291-8