$34.70

FREE
SHIPPING

100% MONEY
BACK GUARANTEE

ONLINE
SUPPORT 24/7

Available on backorder. No lead time available. Please request a quote.
Sku CI07196_1_G
Chem Impex
Get Bulk Quote

Product Information

Product Name
5-Bromouridine
Brand Name
Chem Impex
Product Number
07196
CAS
957-75-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
91494
IUPAC Name
5-bromo-1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidine-2,4-dione
InChI Key
AGFIRQJZCNVMCW-UAKXSSHOSA-N
SMILES
C1=C(C(=O)NC(=O)N1C@H2C@@H(C@@H(C@H(O2)CO)O)O)Br

Application

5-Bromouridine is widely utilized in research focused on:

Antiviral Research: This compound is studied for its potential to inhibit viral replication, making it a valuable tool in developing antiviral therapies.

Nucleoside Analog Development: As a nucleoside analog, it is used in the synthesis of modified RNA molecules, which can help in understanding RNA function and regulation.

Biochemical Assays: It serves as a substrate in various biochemical assays, aiding researchers in studying enzyme activities and interactions in cellular processes.

Gene Expression Studies: 5-Bromouridine is employed in experiments to analyze gene expression and RNA processing, providing insights into genetic regulation mechanisms.

Pharmaceutical Formulations: The compound is explored in drug formulation research, particularly in creating therapies that target specific RNA pathways, offering potential advantages over traditional treatments.

References

Synthesis of New Uracil Derivatives with Antiviral and Anticancer Potential

Publication Name: Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology
Publication Date: 2025-06
DOI: 10.1134/s1990747825700199

Endogenous aldehyde-induced DNA–protein crosslinks are resolved by transcription-coupled repair

Publication Name: Nature Cell Biology
Publication Date: 2024-04-10
DOI: 10.1038/s41556-024-01401-2

A novel, small anti-HBV compound reduces HBsAg and HBV-DNA by destabilizing HBV-RNA

Publication Name: Journal of Gastroenterology
Publication Date: 2024-02-05
DOI: 10.1007/s00535-023-02070-y

N6-methyladenosine modification—a key player in viral infection

Publication Name: Cellular & Molecular Biology Letters
Publication Date: 2023-10-12
DOI: 10.1186/s11658-023-00490-5

Studying Nucleic Acid-Ligand Binding by X-Ray Crystallography

Publication Name: Handbook of Chemical Biology of Nucleic Acids
Publication Date: 2023
DOI: 10.1007/978-981-19-9776-1_13