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Sku CI00871_100_MG
Chem Impex
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Product Information

Product Name
2',3'-Dideoxycytidine
Brand Name
Chem Impex
Product Number
00871
CAS
7481-89-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
24066
IUPAC Name
4-amino-1-(2R,5S)-5-(hydroxymethyl)oxolan-2-ylpyrimidin-2-one
InChI Key
WREGKURFCTUGRC-POYBYMJQSA-N
SMILES
C1CC@@H(OC@@H1CO)N2C=CC(=NC2=O)N

Application

2',3'-Dideoxycytidine is widely utilized in research focused on:

Antiviral Therapy: This compound is primarily used in the treatment of HIV, where it acts as a nucleoside reverse transcriptase inhibitor, helping to reduce viral load and improve patient outcomes.

Research in Cancer Treatment: It has shown potential in cancer research, particularly in studies targeting specific types of leukemia and lymphoma, by disrupting DNA synthesis in rapidly dividing cells.

Development of Antiviral Drugs: The compound serves as a crucial building block in the synthesis of new antiviral agents, aiding researchers in developing more effective treatments against various viral infections.

Studying Nucleic Acid Metabolism: It is used in laboratory settings to investigate the metabolism of nucleic acids, providing insights into cellular processes and the mechanisms of drug action.

Formulating Combination Therapies: Researchers explore its use in combination with other antiretroviral drugs to enhance efficacy and reduce the likelihood of resistance in viral infections.

References

Zalcitabine induces ferroptosis in multiple myeloma through the TFAM–cGAS–STING–SLC7A11 axis

Publication Name: Journal of Translational Medicine
Publication Date: 2026-01-27
DOI: 10.1186/s12967-026-07749-3

VPS34-IN1 potentiates STING-dependent activation in human CAL-1 cells

Publication Name: Cellular & Molecular Biology Letters
Publication Date: 2026-01-24
DOI: 10.1186/s11658-025-00841-4

Immune remodeling via mitochondria-dependent STING activation enhances cabozantinib response in hepatocellular carcinoma

Publication Name: Journal of experimental & clinical cancer research : CR
Publication Date: 2026-01-09
DOI: 10.1186/s13046-025-03632-z

Dimethyl fumarate reprograms cervical cancer cells to enhance antitumor immunity by activating mtDNA-cGAS-STING pathway

Publication Name: Journal of Biomedical Science
Publication Date: 2025-10-20
DOI: 10.1186/s12929-025-01187-x