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Sku CI00105_100_G
Chem Impex
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Product Information

Product Name
2'-Deoxycytidine hydrochloride
Brand Name
Chem Impex
Product Number
00105
CAS
3992-42-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
107488
IUPAC Name
4-amino-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidin-2-one;hydrochloride
InChI Key
LTKCXZGFJFAPLY-OERIEOFYSA-N
SMILES
C1C@@H(C@H(OC@H1N2C=CC(=NC2=O)N)CO)O.Cl

Application

2'-Deoxycytidine hydrochloride is widely utilized in research focused on:

DNA Synthesis: This compound serves as a building block in the synthesis of DNA, making it essential for genetic research and biotechnology applications.

Antiviral Research: It is used in studies aimed at developing antiviral therapies, particularly for viral infections like HIV, due to its role in nucleoside analogs.

Cell Culture: Researchers incorporate it into cell culture media to support the growth of various cell lines, aiding in cancer research and drug development.

Genetic Engineering: The compound is crucial in CRISPR and other gene-editing technologies, allowing scientists to manipulate genetic material effectively.

Pharmaceutical Development: It is explored in the formulation of nucleoside-based drugs, providing therapeutic options for various diseases, including cancer.

References

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Analysis of DNA Methylation Content and Patterns in Plants

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2018
DOI: 10.1007/978-1-4939-7398-9_24

Detection of Histone Modification Dynamics during the Cell Cycle by MS-Based Proteomics

Publication Name: Methods in Molecular Biology
Publication Date: 2018
DOI: 10.1007/978-1-4939-8663-7_4

The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleoside

Publication Name: Cytotechnology
Publication Date: 2017-03-02
DOI: 10.1007/s10616-017-0066-7