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ARV-825, 98%|9173846|1818885-28-7

ARV-825, 98%

Cat. No JK9173846_25_MG
J&K Chemical

Product Information

Product Name
ARV-825, 98%
Brand Name
J&K
Product Number
9173846
CAS
1818885-28-7
Molecular Formula
C46H47ClN8O9S
Molecular Weight
923.43
Certificate of Analysis (COA)​
COA not found

General Information

Synonyms
(6S)-4-(4-chlorophenyl)-N-4-2-2-2-2-2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1
PubChem CID
92044400
IUPAC Name
2-(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo8.3.0.02,6trideca-2(6),4,7,10,12-pentaen-9-yl-N-4-2-2-2-2-2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-ylaminoethoxyethoxyethoxyethoxyphenylacetamide
InChI Key
RWLOGRLTDKDANT-TYIYNAFKSA-N
SMILES
CC1=C(SC2=C1C(=NC@H(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)OCCOCCOCCOCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8=CC=C(C=C8)Cl)C

Properties

Density
1.47

Safety Information

Storage Condition
Store at 2-8℃

References Data Source From Pubchem

Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain
Publication Name: ACS Medicinal Chemistry Letters
Publication Date: 2024-01-26
DOI: 10.1021/acsmedchemlett.3c00490

Current advances of small molecule E3 ligands for proteolysis-targeting chimeras design
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2023-08-05
DOI: 10.1016/j.ejmech.2023.115444

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer
Publication Name: Science Translational Medicine
Publication Date: 2023-06-21
DOI: 10.1126/scitranslmed.add7872

PROTACS: A technology with a gold rush-like atmosphere
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2023-02-05
DOI: 10.1016/j.ejmech.2022.115037

A bibliometric analysis of PROTAC from 2001 to 2021
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2022-12-15
DOI: 10.1016/j.ejmech.2022.114838

ARV-825, 98%

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