Dimethylenastron, 98%, a potent Eg5 inhibitor, with an IC50 of 200 nM

Name: Dimethylenastron, 98%, a potent Eg5 inhibitor, with an IC50 of 200 nM | 863774-58-7
Brand: J&K Chemical
SKU: JK804505_10_MG
Price: 125.4 USD
Availability: OutOfStock

Cat. No JK804505_10_MG

Vendor: J&K Chemical

Product Information

Product Name

Dimethylenastron, 98%, a potent Eg5 inhibitor, with an IC50 of 200 nM

Brand Name

J&K

Product Number

804505

CAS

863774-58-7

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

11609157

IUPAC Name

4-(3-hydroxyphenyl)-7,7-dimethyl-2-sulfanylidene-3,4,6,8-tetrahydro-1H-quinazolin-5-one

InChI Key

RUOOPLOUUAYNPY-UHFFFAOYSA-N

SMILES

CC1(CC2=C(C(NC(=S)N2)C3=CC(=CC=C3)O)C(=O)C1)C

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Target Class Profiling of Small-Molecule Methyltransferases

Publication Name: ACS Chemical Biology

Publication Date: 2023-03-28

DOI: 10.1021/acschembio.3c00124

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Publication Name: Proceedings of the National Academy of Sciences of the United States of America

Publication Date: 2020-11-23

DOI: 10.1073/pnas.2005463117

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening

Publication Name: SLAS discovery : advancing life sciences R & D

Publication Date: 2020-01

DOI: 10.1177/2472555219873068

Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors

Publication Name: Bioorganic & Medicinal Chemistry

Publication Date: 2019-12-01

DOI: 10.1016/j.bmc.2019.115126

A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein

Publication Name: Molecular Pharmacology

Publication Date: 2019-11

DOI: 10.1124/mol.119.115964

Dimethylenastron, 98%, a potent Eg5 inhibitor, with an IC50 of 200 nM

Product Information

General Information

Safety Information

References Data Source From Pubchem

Target Class Profiling of Small-Molecule Methyltransferases

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening

Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors

A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein