PD153035, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively

Name: PD153035, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively | 153436-54-5
Brand: J&K Chemical
SKU: JK292869_5_MG
Price: 57.0 USD
Availability: OutOfStock

Cat. No JK292869_5_MG

Vendor: J&K Chemical

Product Information

Product Name

PD153035, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively

Brand Name

J&K

Product Number

292869

CAS

153436-54-5

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

4705

IUPAC Name

N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine

InChI Key

LSPANGZZENHZNJ-UHFFFAOYSA-N

SMILES

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

FN1 as a key gene in modulating the integrin cell surface pathway in breast cancer

Publication Name: Medical oncology (Northwood, London, England)

Publication Date: 2026-02-25

DOI: 10.1007/s12032-025-03102-8

Comprehensive analysis of FAM83B in pan-cancer and preliminary exploration in esophageal squamous cell carcinoma

Publication Name: Journal of Molecular Histology

Publication Date: 2025-05-26

DOI: 10.1007/s10735-025-10452-0

Epidermal growth factor increases cystathionine β-synthase expression in cultured embryonic spinal cord cells

Publication Name: In Vitro Cellular & Developmental Biology - Animal

Publication Date: 2025-04

DOI: 10.1007/s11626-025-01043-0

Polybrominated diphenyl ether flame retardants inhibit growth factor-induced activation of EGFR by binding to its extracellular domain

Publication Name: Archives of Toxicology

Publication Date: 2024-12-12

DOI: 10.1007/s00204-024-03926-9

IL-1β-activated PI3K/AKT and MEK/ERK pathways coordinately promote induction of partial epithelial–mesenchymal transition

Publication Name: Cell communication and signaling : CCS

Publication Date: 2024-08-08

DOI: 10.1186/s12964-024-01775-8

PD153035, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively

Product Information

General Information

Safety Information

References Data Source From Pubchem

FN1 as a key gene in modulating the integrin cell surface pathway in breast cancer

Comprehensive analysis of FAM83B in pan-cancer and preliminary exploration in esophageal squamous cell carcinoma

Epidermal growth factor increases cystathionine β-synthase expression in cultured embryonic spinal cord cells

Polybrominated diphenyl ether flame retardants inhibit growth factor-induced activation of EGFR by binding to its extracellular domain

IL-1β-activated PI3K/AKT and MEK/ERK pathways coordinately promote induction of partial epithelial–mesenchymal transition