IWP-2, 97%, an inhibitor of Wnt processing and secretion with IC50 of 27 nM

Name: IWP-2, 97%, an inhibitor of Wnt processing and secretion with IC50 of 27 nM | 686770-61-6
Brand: J&K Chemical
SKU: JK1432349_10_MG
Price: 96.9 USD
Availability: OutOfStock

Cat. No JK1432349_10_MG

Vendor: J&K Chemical

Product Information

Product Name

IWP-2, 97%, an inhibitor of Wnt processing and secretion with IC50 of 27 nM

Brand Name

J&K

Product Number

1432349

CAS

686770-61-6

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

2155128

IUPAC Name

N-(6-methyl-1,3-benzothiazol-2-yl)-2-(4-oxo-3-phenyl-6,7-dihydrothieno3,2-dpyrimidin-2-yl)sulfanylacetamide

InChI Key

WRKPZSMRWPJJDH-UHFFFAOYSA-N

SMILES

CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

Safety Information

Storage Condition

Freezer -20℃

References

Flavin-containing monooxygenase 2 confers cardioprotection in ischemia models through its disulfide bond catalytic activity

Publication Name: The Journal of clinical investigation

Publication Date: 2024-10-31

DOI: 10.1172/jci177077

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

Publication Name: Cancer Letters

Publication Date: 2023-08-01

DOI: 10.1016/j.canlet.2023.216284

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

Publication Name: Science Translational Medicine

Publication Date: 2023-06-21

DOI: 10.1126/scitranslmed.add7872

Target Class Profiling of Small-Molecule Methyltransferases

Publication Name: ACS Chemical Biology

Publication Date: 2023-03-28

DOI: 10.1021/acschembio.3c00124

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

Publication Name: PLOS Pathogens

Publication Date: 2022-01-10

DOI: 10.1371/journal.ppat.1010166

IWP-2, 97%, an inhibitor of Wnt processing and secretion with IC50 of 27 nM

Product Information

General Information

Safety Information

References

Flavin-containing monooxygenase 2 confers cardioprotection in ischemia models through its disulfide bond catalytic activity

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

Target Class Profiling of Small-Molecule Methyltransferases

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages