IWR-1, 98%, a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway

Name: IWR-1, 98%, a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway | 1127442-82-3
Brand: J&K Chemical
SKU: JK1189408_5_MG
Price: 57.0 USD
Availability: InStock

Cat. No JK1189408_5_MG

Vendor: J&K Chemical

Product Information

Product Name

IWR-1, 98%, a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway

Brand Name

J&K

Product Number

1189408

CAS

1127442-82-3

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

44483163

IUPAC Name

4-(1R,2S,6R,7S)-3,5-dioxo-4-azatricyclo5.2.1.02,6dec-8-en-4-yl-N-quinolin-8-ylbenzamide

InChI Key

ZGSXEXBYLJIOGF-ALFLXDJESA-N

SMILES

C1C@@H2C=CC@H1C@@H3C@H2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Hepatic lipid metabolism disorders and immunotoxicity induced by cysteamine in early developmental stages of zebrafish

Publication Name: Toxicology

Publication Date: 2023-07

DOI: 10.1016/j.tox.2023.153555

Development of a penetratin-conjugated stapled peptide that inhibits Wnt/β-catenin signaling

Publication Name: Bioorganic & Medicinal Chemistry

Publication Date: 2022-11-01

DOI: 10.1016/j.bmc.2022.117021

Small-Molecule Inhibitors of Tankyrases as Prospective Therapeutics for Cancer

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2022-03-21

DOI: 10.1021/acs.jmedchem.1c02139

Hematopoietic stem cell and immunotoxicity in zebrafish embryos induced by exposure to Metalaxyl-M

Publication Name: The Science of the total environment

Publication Date: 2022-02-25

DOI: 10.1016/j.scitotenv.2021.152102

Linderapyrone: A Wnt signal inhibitor isolated from Lindera umbellata

Publication Name: Bioorganic & Medicinal Chemistry Letters

Publication Date: 2021-08-01

DOI: 10.1016/j.bmcl.2021.128161

IWR-1, 98%, a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway

Product Information

General Information

Safety Information

References Data Source From Pubchem

Hepatic lipid metabolism disorders and immunotoxicity induced by cysteamine in early developmental stages of zebrafish

Development of a penetratin-conjugated stapled peptide that inhibits Wnt/β-catenin signaling

Small-Molecule Inhibitors of Tankyrases as Prospective Therapeutics for Cancer

Hematopoietic stem cell and immunotoxicity in zebrafish embryos induced by exposure to Metalaxyl-M

Linderapyrone: A Wnt signal inhibitor isolated from Lindera umbellata