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Sku CI30043_5_G
Chem Impex
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Product Information

Product Name
2',3',5'-tri-O-Acetyluridine
Brand Name
Chem Impex
Product Number
30043
CAS
4105-38-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
20058
IUPAC Name
(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-ylmethyl acetate
InChI Key
AUFUWRKPQLGTGF-FMKGYKFTSA-N
SMILES
CC(=O)OCC@@H1C@H(C@H(C@@H(O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)C

Application

2',3',5'-tri-O-Acetyluridine is widely utilized in research focused on:

Nucleic Acid Research: This compound serves as a key building block in the synthesis of modified nucleotides, which are essential for studying RNA structure and function.

Drug Development: It plays a significant role in the formulation of antiviral agents, particularly those targeting RNA viruses, enhancing their efficacy and stability.

Biotechnology: Used in the production of RNA-based therapeutics, it helps in the development of mRNA vaccines and gene therapies, addressing critical health challenges.

Analytical Chemistry: This chemical is employed as a standard in chromatographic techniques, aiding in the accurate analysis of nucleosides and nucleotides in various samples.

Pharmaceutical Formulations: Its acetyl groups improve solubility and bioavailability, making it a valuable ingredient in the design of oral drug formulations.

References Data Source From Pubchem

A case of folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy regimen associated neurotoxicity and review of literature

Publication Name: BMC Neurology
Publication Date: 2025-11-25
DOI: 10.1186/s12883-025-04416-w

Involvement of uridine in brain and gut health: insights into its neuroprotective potential via the gut-brain axis

Publication Name: Pharmacological reports : PR
Publication Date: 2025-10-10
DOI: 10.1007/s43440-025-00788-5

Fluorouracil

Publication Name: Reactions Weekly
Publication Date: 2025-09-06
DOI: 10.1007/s40278-025-89375-8

Uridine as a hub in cancer metabolism and RNA biology

Publication Name: Experimental & Molecular Medicine
Publication Date: 2025-08-14
DOI: 10.1038/s12276-025-01402-7

Movement disorders associated with diarrhoea

Publication Name: Journal of neural transmission (Vienna, Austria : 1996)
Publication Date: 2025-07-17
DOI: 10.1007/s00702-025-02924-0