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Product Information

Product Name
2-Fluoropyridine-3-boronic acid
Brand Name
Chem Impex
Product Number
28818
CAS
174669-73-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2783270
IUPAC Name
(2-fluoro-3-pyridinyl)boronic acid
InChI Key
YUHZIUAREWNXJT-UHFFFAOYSA-N
SMILES
B(C1=C(N=CC=C1)F)(O)O

Application

2-Fluoropyridine-3-boronic acid is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer and other diseases.

Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, to create complex organic molecules, making it invaluable for chemists in the field of organic synthesis.

Material Science: The compound is used in the production of advanced materials, including polymers and coatings, that require specific chemical properties for enhanced performance.

Agricultural Chemistry: It plays a role in the development of agrochemicals, contributing to the formulation of herbicides and pesticides that are more effective and environmentally friendly.

Analytical Chemistry: This chemical is utilized in various analytical techniques, aiding researchers in the detection and quantification of other compounds in complex mixtures.

References

Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expression

Publication Name: EJNMMI Radiopharmacy and Chemistry
Publication Date: 2019-01-10
DOI: 10.1186/s41181-018-0054-z

Synthesis of Chk1 Inhibitor GDC-0425

Publication Name: Synfacts
Publication Date: 2015-08-18
DOI: 10.1055/s-0034-1378763

Synthesis of novel N-aryl-4-[6-(2-fluoropyridin-3-yl)quinazolin-2-yl]-piperazine-1-carboxamide or -carbothioamide derivatives and their antimicrobial activity

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2015-01
DOI: 10.1007/s10593-015-1660-2

Metal-Catalyzed Cross-Coupling Reactions in the Decoration of Pyridines

Publication Name: Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions
Publication Date: 2015
DOI: 10.1007/7081_2015_141

First Identification of Boronic Species as Novel Potential Inhibitors of the Staphylococcus aureus NorA Efflux Pump

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2014-02-19
DOI: 10.1021/jm401808n