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Chem Impex
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Product Information

Product Name
Na-Boc-Ne-2-chloro-Z-L-lysine
Brand Name
Chem Impex
Product Number
00647
CAS
54613-99-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7269331
IUPAC Name
(2S)-6-(2-chlorophenyl)methoxycarbonylamino-2-(2-methylpropan-2-yl)oxycarbonylaminohexanoic acid
InChI Key
ATUMDPHEFWGCJF-HNNXBMFYSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCCCNC(=O)OCC1=CC=CC=C1Cl)C(=O)O

Application

Na-Boc-Ne-2-chloro-Z-L-lysine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its protective groups allow for selective reactions, enhancing the efficiency of peptide assembly.

Drug Development: It plays a significant role in the creation of novel therapeutic agents. By modifying the lysine residue, researchers can improve the pharmacological properties of drug candidates, leading to more effective treatments.

Bioconjugation: The compound is used in bioconjugation processes, where it helps attach drugs or imaging agents to biomolecules. This application is crucial in targeted drug delivery systems, enhancing the specificity and efficacy of treatments.

Research in Protein Engineering: It aids in the design of modified proteins with enhanced stability and activity. This is particularly beneficial in the fields of biotechnology and enzyme engineering, where tailored proteins can lead to innovative solutions.

Analytical Chemistry: The compound is utilized in analytical methods for studying amino acid sequences and modifications. Its unique structure allows for precise identification and quantification of peptides in complex mixtures.

References Data Source From Pubchem

In Situ Neutralization Protocols for Boc-SPPS

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0227-0_3

Semisynthesis of Membrane-Attached Proteins Using Split Inteins

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2017
DOI: 10.1007/978-1-4939-6451-2_7

Synthesis and SAR Studies of Bisthiourea Derivatives of Dipeptides Lys/lys-Asp, Lys/lys-Trp Conjugated Benzo[d]isoxazole as Promising Antioxidants

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2016-09-29
DOI: 10.1007/s10989-016-9557-1

Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids

Publication Name: Nature Communications
Publication Date: 2014-10-06
DOI: 10.1038/ncomms6079

Design, Synthesis, and Study of Fluorinated Proteins

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2014
DOI: 10.1007/978-1-4939-1486-9_5