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Sku CI04314_1_G
Chem Impex
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Product Information

Product Name
Fmoc-D-aspartic acid a-tert-butyl ester
Brand Name
Chem Impex
Product Number
04314
CAS
134098-70-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7019703
IUPAC Name
(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2-methylpropan-2-yl)oxy-4-oxobutanoic acid
InChI Key
VZXQYACYLGRQJU-LJQANCHMSA-N
SMILES
CC(C)(C)OC(=O)C@@H(CC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-D-aspartic acid a-tert-butyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. Its stability under various conditions makes it a preferred choice in the field.

Drug Development: In pharmaceutical research, it plays a crucial role in the design of peptide-based drugs, particularly those targeting neurological disorders, by providing a stable structure that can be easily modified.

Bioconjugation: This chemical is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutic agents.

Research in Neuroscience: It is instrumental in studying neurotransmitter systems, as its derivatives can mimic natural neurotransmitters, aiding in the development of treatments for conditions like depression and anxiety.

Material Science: The compound is also explored in the creation of smart materials, where its properties can be utilized to develop responsive systems for drug delivery or biosensing applications.

References

The Staudinger Reaction

Publication Name: Science of Synthesis
Publication Date: 2007