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Sku CI30040_5_G
Chem Impex
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Product Information

Product Name
2-Chloroadenosine
Brand Name
Chem Impex
Product Number
30040
CAS
146-77-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
8974
IUPAC Name
(2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI Key
BIXYYZIIJIXVFW-UUOKFMHZSA-N
SMILES
C1=NC2=C(N=C(N=C2N1C@H3C@@H(C@@H(C@H(O3)CO)O)O)Cl)N

Application

2-Chloroadenosine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in the synthesis of various antiviral and anticancer agents, providing researchers with a pathway to develop targeted therapies.

Cell Signaling Studies: It is used to investigate adenosine receptors in cellular signaling pathways, helping scientists understand their roles in processes like inflammation and immune response.

Neuroscience Research: The compound is instrumental in studying neuroprotective effects, particularly in models of neurodegenerative diseases, offering insights into potential treatments.

Biochemical Assays: 2-Chloroadenosine is employed in assays to measure enzyme activity related to nucleotide metabolism, aiding in the development of diagnostic tools.

Drug Interaction Studies: It helps researchers explore interactions between drugs and adenosine receptors, which is crucial for optimizing therapeutic regimens and minimizing side effects.

References Data Source From Pubchem

Astrocytes Control Norepinephrine Signaling in the Brain

Publication Name: Neuroscience Bulletin
Publication Date: 2025-11-20
DOI: 10.1007/s12264-025-01551-9

Deficiency of KMT2D causes autistic-like behavior in mice and zebrafish

Publication Name: Communications Biology
Publication Date: 2025-08-29
DOI: 10.1038/s42003-025-08635-2

Purinergic receptors in atherosclerosis: implications for pathophysiology and therapeutic strategies

Publication Name: Journal of Physiology and Biochemistry
Publication Date: 2025-07-16
DOI: 10.1007/s13105-025-01108-4