The Ullman reaction was discovered by Ullman in 1903. It usually refers to a copper-catalyzed cross-coupling reaction between an aryl halide and a nucleophile such as oxygen, nitrogen, sulfur, phosphorus or carbon. This reaction not only requires the use of an excess of copper catalyst, but also requires high temperature and strong alkali reaction conditions. For more than a hundred years, people have been working on improving the reaction conditions, reducing the amount of copper, and expanding the scope of substrates. At the end of the 20th century, Ma Dawei et al. first discovered that α-amino acid ligands can promote copper-catalyzed cross-coupling reactions under mild conditions. The copper/proline catalytic system can make aryl halides and substituted sodium sulfinates react under mild conditions. Coupling occurs to form aryl sulfones.
Bailingwei can provide reagents required for the design and synthesis research of a variety of sulfur-containing compounds to facilitate the development of organic sulfur chemistry:
Full range: covering reagents for C-S bond formation, sulfonyl halides, sulfonyl hydrazides, thioethers, thiols, thiophenols, sulfonate esters, sulfonic acids (salts), thiocyanates, anilines and other molecular building blocks, catalysts And ligands, organometallic reagents, synthetic reagents and other series, we can also provide supporting inorganic reagents, ultra-dry solvents, nuclear magnetic solvents and common instrument consumables;
New products: New organic sulfur reagents developed by scientific researchers in this field can be provided;
Good quality: high purity, strict quality control, and stable batch quality.

Reagents for C-S bond formation

Sulfonyl halide

Thiols and thiophenols

Sulfide and disulfide

Thiocyanates and isothiocyanates

Sulfonyl hydrazide

Sulfone and sulfoxide

Sulfonic acid (salt) and sulfinic acid (salt)

Sulfonates and sulfinates

Anilines

Catalysts and ligands

Synthetic reagents

Organometallic reagents

General product

Ma Dawei is an academician of the Chinese Academy of Sciences, a researcher and doctoral supervisor at the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, and the director of the State Key Laboratory of Organic Chemistry of Life. [1-2] Chairman of the Academic Committee of the National Key Laboratory of Innovative Drugs for Antiviral Infectious Diseases. [twenty two]
After graduating from the Chemistry Department of Shandong University in 1984, he was admitted to the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences as a postgraduate student, and received a doctorate in science in 1989. In 1990, he went to the University of Pittsburgh and the Mayo Medical Center in the United States to conduct postdoctoral research. In 1994, he was selected into the first batch of Chinese scientists. He joined the Hundred Talents Program of the Academy of Sciences and returned to work at the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences; he was hired as a long-term part-time professor by Fudan University in 1997, and received funding from the National Science Fund for Distinguished Young Scholars in the same year [3]; in 1998, he received the Outstanding Young Scholar Award from the Qiushi Science and Technology Foundation [4]; In 2007, he won the first WuXi AppTec Life Chemistry Research Award[5]; in 2018, he won the third Future Science Award for Material Science[6]. On November 22, 2019, he was elected as an academician of the Chinese Academy of Sciences. [2]
Research directions include: total synthesis and structure-activity relationships of complex natural products with important physiological activities; small molecule modulators for special targets such as G-protein coupled receptors, protein kinases, proteolytic enzymes and apoptosis processes The discovery of organic synthesis methodologies and their application in the synthesis of bioactive molecules.