Mitochondria: Essential Organelles for Eukaryotic Cells
Mitochondria are fundamental organelles in eukaryotic cells. Positively charged dyes can selectively localize within mitochondria, making them widely used for labeling mitochondria in living cells and providing novel research methods for studying mitochondrial metabolic processes.
IR-780 Ethyl Iodide: Precision Mitochondrial Targeting
IR-780 ethyl iodide (λex=780 nm, λem=830 nm) enables precise mitochondrial localization. It features multiple modification sites, allowing the construction of activatable fluorescent probes and the design of novel mitochondrial-targeted probes. It is utilized in cells and living organisms to detect reactive biomolecules and organ damage caused by diseases.
Additional Applications in Biomedical Research
Additionally, IR-780 ethyl iodide demonstrates excellent staining effects on sentinel lymph nodes with high stability. Through the activity of the HIF-1α/glycolysis-dependent mitochondrial transporter ABCB10, it is applied for the specific characterization of human CSCs. IR-780 ethyl iodide readily accumulates in the mitochondria of cancer cells and is employed in cancer diagnosis and treatment.
|
Professor Qin Wang is affiliated with the College of Chemistry and Environmental Science at Shaanxi University of Technology. |
|
| Her research focuses on the construction and application of nano fluorescent probes. She has published multiple research papers in SCI-indexed journals, including nine as the first author. Additionally, she has participated in the completion of two National Natural Science Foundation projects. |
Related Products
- IR-780 Ethyl iodide, 95% （CAS 124591-86-2）
Notice for Bulk/Industrial Orders
To ensure you receive the most accurate pricing and terms for your specific needs, all purchases require a custom quote.
Please contact our sales team to discuss your requirements and receive a formal quotation.
We appreciate your interest and look forward to supporting your large-scale projects.
艳 李
