3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee)

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Sku 07-5611-50MG
STREM
Technical Notes:
1.Mannich Reaction: The asymmetric addition of the present HWE reagents to N-ca rbamoyl imines
generated in situ was achieved. The corresponding Mannich adducts can be further transformed to aza- MBH type products in good to excellent enantioselectivities.
References:
1. Chem. Sci., 2011, 2, 1918-1921.