The Unique Appeal of Gold Nanoclusters Gold nanoclusters have attracted widespread attention in fields such as catalysis, optics, and the exploration of structure–property relationships at the atomic level, due to their ultra‑small size, varied metal‑ligand interactions, and precisely defined atomic structures. Constructing gold nanoclusters with open sites has long been...

Mass spectrometry instrumentation now finds applications across more than 60% of economic sectors and has been explicitly recognized as an industrial key enabling technology with fundamental and widespread utility. Among its critical supporting reagents, mass spectrometry derivatization reagents represent a breakthrough opportunity for achieving technological leapfrogging in analytical detection. TMT (Tandem Mass Tag) is a...

Cytochrome P450 3A4 (CYP3A4) is the most important cytochrome P450 enzyme for drug metabolism in humans. Its activity directly determines the efficacy and safety of over 50% of clinical pharmaceuticals. Traditional detection methods relying on mass spectrometry are limited by high costs and complex workflows, restricting their deep application in complex biological...