$48.00
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Sku 15-0137-250MG
STREM
| Technical Notes: 1. Biaryl bisphos phine ligand with narrow dihedral angle. The SEGPHOS® ligand has been applied to a variety of metal catalyzed reactions. In many cases, yields and enantios electivities, exceed results obtained earlier using BINAP 2.As ruthenium complex, SEGPHC S® generally gives higher levels of chiral induction in as ymmetric hydrogenations of a,ß,and y-functionalized ketones. See ruthenium complexes 44-0096, 44-0518, 44-01 68 3.Used in Rh-catalyzed transformations such as: (a) 1,4-addition of boronic acids to coumarins, (b) addition of titanium reagents to imines,' (c) cotrimerization of alkenes and acetylenes,o (d) double [2+2+2] cycloaddition," (e) indanone formation.a, 4.Used in Pd-catalyzed transformations such as: (a) cycloaddition of 1,6-enyne, (b) arylative cyclization of allenyl aldehydes with boronic acids,13 (c) synthesis of chromans. 5.Used in Cu-catalyzed transformations such as: (a) nitroso Diels-Alder,' (b) reductive aldol 6.condensation, (c) conjugate reduction of unsaturated sulfones, and phophonates 7.Iridium-catalyzed asymmetric hydrogenation of quinolines activated by chloroformates 8.Iridium-catalyzed asymmetric transfer hydrog enation used in polyketide construction. 9.Rhodium-catalyzed asymmetric hydroarylation of 3-pyrrolines. 10.P alladium-catalyzed regio- and enantioselective dearomatization of pyrroles to 2H-pyrroles.' Rhodium-catalyzed as ymmetric synthesis of cyclopentanols.0 11. Silver-catalyzed as ymmetric Mannich-type reac tion. |
