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Chem Impex
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Product Information

Product Name
2-Iminothiolane hydrochloride
Brand Name
Chem Impex
Product Number
02326
CAS
4781-83-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
13166855
IUPAC Name
thiolan-2-imine;hydrochloride
InChI Key
ATGUDZODTABURZ-UHFFFAOYSA-N
SMILES
C1CC(=N)SC1.Cl

Application

2-Iminothiolane hydrochloride is widely utilized in research focused on:

Bioconjugation: This compound is often used to create stable linkages between biomolecules, such as proteins and antibodies, enhancing their functionality in drug delivery systems.

Protein Labeling: It serves as a valuable reagent for labeling proteins with fluorescent tags, which is essential in various imaging and diagnostic applications.

Antibody Modification: Researchers apply it to modify antibodies for improved specificity and binding affinity, which is crucial in therapeutic applications and diagnostics.

Cellular Studies: The compound is used in cellular assays to study protein interactions and cellular processes, providing insights into disease mechanisms.

Drug Development: It plays a role in the development of new pharmaceuticals by facilitating the synthesis of complex molecules, streamlining the drug discovery process.

References

Multicomponent reaction-based combinatorial chemistry for accelerating the discovery of therapeutic protein and nucleic acid delivery materials

Publication Name: NPG Asia Materials
Publication Date: 2025-04-04
DOI: 10.1038/s41427-025-00595-7

Oxygen-generating gelatin-based cryogels for enhanced hemostasis and skin wound healing

Publication Name: Macromolecular Research
Publication Date: 2025-02-19
DOI: 10.1007/s13233-025-00373-y

Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses

Publication Name: Journal of Nanobiotechnology
Publication Date: 2025-02-04
DOI: 10.1186/s12951-025-03104-8

Synthesis of Hybrid Peptide-Based Materials

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4562-8_17

Nanoplatelets modified with RVG for targeted delivery of miR-375 and temozolomide to enhance gliomas therapy

Publication Name: Journal of Nanobiotechnology
Publication Date: 2024-10-15
DOI: 10.1186/s12951-024-02895-6