Dess–Martin Oxidation refers to the oxidation of alcohols to the corresponding carbonyl compounds using Dess–Martin periodinane (DMP). The reaction is named after American chemists Daniel Benjamin Dess and James Cullen Martin. Dess–Martin periodinane (DMP), full name: 1,1,1-triacetoxy-1,1-dihydro-1,2-benziodoxol-3(1H)-one, was developed in 1983 by the aforementioned chemists. The Dess–Martin oxidation can proceed...

Barton Decarboxylation refers to a radical reaction in which a carboxylic acid is first converted into a thiohydroxamate ester (also known as a Barton ester), and then thermally decomposed in the presence of a radical initiator and a suitable hydrogen donor to yield the decarboxylated product. The reaction is named...

Fukuyama Coupling refers to the reaction between organozinc compounds and thioesters under palladium catalysis to produce ketones. This reaction was discovered by Tohru Fukuyama and colleagues in 1998 and is named after him. Fukuyama Coupling has attracted widespread attention for its mild reaction conditions and high functional group compatibility, making...

The Favorskii reaction refers to the nucleophilic addition of terminal alkynes to carbonyl compounds in the presence of a basic medium (e.g., anhydrous potassium hydroxide or sodium amide), yielding propargylic alcohols. The reaction is named after Russian chemist Alexei Yevgrafovich Favorskii, who first reported it. The reaction mechanism involves deprotonation...

The Dakin reaction refers to the transformation of ortho- or para-hydroxy aromatic aldehydes or ketones into corresponding phenols under basic conditions using hydrogen peroxide. This reaction was discovered by Henry Drysdale Dakin in 1909, and is named in his honor. It is an efficient method for synthesizing polyhydroxy aromatic compounds....

The Fleming–Tamao oxidation is a reaction that converts silanes into alcohols using peracids or hydrogen peroxide. The reaction is named after Kohei Tamao and Ian Fleming, who independently reported slightly different versions of this transformation in 1983 and 1984, respectively. Reagents: Hydrogen peroxide or peracid, solvent, fluorinated additives Reactants: Silanes...